Study to Compare Verbal Scores of Children Diagnosed With ASD Who Received Hyperbaric Treatment To Those Who Did Not

Oxford Recovery Center

Status: Completed

Conditions: Autism Spectrum Disorder

Treatments: Device: Hyperbaric Oxygen Therapy

Study type: Observational

Funder types: Other

Identifiers

NCT06043284

OxRS-01-2021

Details and patient eligibility

About

A child's ability to effectively communicate with peers, parents, and caregivers impacts their level of independence and quality of personal relationships. This retrospective study will compare the speech development of participants aged 2 - 17 years that received 40 sessions of HBOT at 2.0 ATA to those who had not. Both groups will have a verbal assessment every six months. There were 32 subjects in the HBO group and 33 subjects in the non-HBO group. The statistical analysis will focus on whether Hyperbaric Oxygen Therapy made a significant difference in Verbal Behavior Milestones Assessment and Placement Program (VB-MAPP) or Assessment of Basic Language and Learning Skills (ABLLS) results.

Full description

Methods: This was a study designed to retrospectively determine any association between hyperbaric oxygen therapy (HBOT) and change in verbal scores in children with autism spectrum disorder (ASD). All children aged 2 to 17 years, diagnosed with ASD who completed a verbal test every six months (either Verbal Behavior Milestones Assessment and Placement Program or the Assessment of Basic Language and Learning Skills), received applied behavioral analysis at Oxford Recovery Center (ORC) were screened for inclusion, some of whom had elected to receive HBOT (at least 40 sessions for 60 minutes at 2.0 ATA).

Enrollment: 65 patients

Sex: All

Ages: 2 to 17 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosed with autism spectrum disorder by a qualified practitioner
• Obtained medical clearance for hyperbaric oxygen therapy
• Received applied behavioral analysis at Oxford Recovery Center
• Received two of the same age appropriate verbal test 6 months apart

Exclusion criteria

• History of seizure disorder
• Diagnosis of genetic or mitochondrial mutation

Trial design

65 participants in 2 patient groups

HBO Treatment Group

Description:

Children diagnosed with autism spectrum disorder received applied behavior therapy and hyperbaric oxygen therapy

Treatment:

Device: Hyperbaric Oxygen Therapy

Control Group

Description:

Children diagnosed with autism spectrum disorder received applied behavioral therapy