Study to Develop a Breath Analyser to Detect Chronic Kidney Disease

University College London (UCL)

Status: Unknown

Conditions: Kidney Diseases

Treatments: Diagnostic Test: breath

Study type: Observational

Funder types: Other

Identifiers

NCT03303222

IRAS 228416

Details and patient eligibility

About

Measure trimethylamine oxide in the breath.

Full description

Organic compounds such as trimethylamine oxide (TMAO) accumulate in the blood of patients with kidney disease, and volatile compounds such as TMAO can be detected in the breath.

The investigators wish to develop a breath analyser to measure volatile compounds, such as TMAO in the breath in patients with kidney disease.

Enrollment: 100 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with kidney disease under the care of Royal Free Hospital

Exclusion criteria

• patients unable to provide informed consent
• patients unable to exhale into breath analyser

Trial design

100 participants in 2 patient groups

patients on dialysis

Description:

patients with kidney disease treated by dialysis

Treatment:

Diagnostic Test: breath

patients with chronic kidney disease

Description:

patients with chronic kidney disease not treated by dialysis

Treatment:

Diagnostic Test: breath