Study to Evaluate the Efficacy and Safety of SLV306 in Subjects With Hypertension

Solvay

Status and phase: Completed; Phase 2

Conditions: Hypertension

Treatments: Drug: Daglutril

Study type: Interventional

Funder types: Industry

Identifiers

NCT00160212

S306.2.008

2004-000305-21

Details and patient eligibility

About

This study is to compare the efficacy and safety of increasing doses of SLV306 with amlodipine.

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• sitting office diastolic blood pressure between 90 and 109 mmHg
• office systolic blood pressure between 140 and 179 mmHg
• mean day-time diastolic 24-h ABPM blood pressure >= 85 mmHg inclusive at baseline

Exclusion criteria

• known secondary hypertension
• decompensated congestive heart failure

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind