Study to Evaluate the Inflammatory Cells Activity in Patients With Persistent Asthma Treated With Montelukast (0476-403)(COMPLETED)

University of Brasilia

Status and phase: Completed; Phase 4

Conditions: Asthma

Treatments: Drug: montelukast sodium; Drug: Comparator: placebo comparator

Study type: Interventional

Funder types: Other

Identifiers

NCT00770900

MK0476-403

2008_563

Details and patient eligibility

About

Verify if the quantitative parameters of the eosinophils activation and phagocyte system function show a predictive value for clinical response and prognostic in patients with persistent asthma treated with montelukast

Enrollment: 83 patients

Sex: All

Ages: 2 to 18 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients Between 2-18 Years With Persistent Asthma

Exclusion criteria

Patients > 18 Years Old And < 2 Years Old

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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83 participants in 2 patient groups, including a placebo group

Montelukast

Experimental group

Description:

Asthmatic children and teenagers took montelukast daily.

Treatment:

Drug: montelukast sodium

Placebo

Placebo Comparator group

Description:

Placebo to montelukast tablet daily.

Treatment:

Drug: Comparator: placebo comparator