Study to Investigate Sleep Apnea Patients at Altitude

University of Zurich (UZH) logo

University of Zurich (UZH)

Status

Completed

Conditions

Obstructive Sleep Apnea Syndrome

Treatments

Other: altitude exposure

Study type

Interventional

Funder types

Other

Identifiers

NCT00514826
EK1413

Details and patient eligibility

About

The purpose of the study is to investigate the effect of an altitude sojourn on patients with the obstructive sleep apnea syndrome

Full description

Previous observations do not allow to draw firm conclusions on the effect of altitude sojourn on sleep, breathing and daytime performance in patients with the obstructive sleep apnea syndrome. Furthermore, the susceptibility of sleep apnea patients to high altitude related illness is not known. Therefore, the purpose is to study untreated patients with obstructive sleep apnea syndrome living at low altitude during a sojourn of a few days at moderate altitude in order to evaluate the physiologic effects of hypobaric hypoxia in these patients. We hypothesize that: 1. Sleep and nocturnal breathing disturbances in untreated OSA patients are more pronounced at moderate altitude compared to low altitude. 2. The increase in sleep related breathing disturbances at moderate altitude is due to an increase in central apnea/hypopnea

Enrollment

40 estimated patients

Sex

All

Ages

20+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Obstructive sleep apnea syndrome based on symptoms and a sleep study

Exclusion criteria

  • Sleep disorders other than obstructive sleep apnea syndrome
  • Other than mild, stable cardiovascular disease
  • Other than mild lung disease
  • Chronic rhinitis, previous uvulopalatopharyngoplasty
  • Treatment with drugs that affect respiratory center drive
  • Internal, neurologic or psychiatric disease that interferes with sleep quality
  • Previous intolerance to moderate or low altitude < 2600m

Trial contacts and locations

0

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location

Resources

© Copyright 2024 Veeva Systems