Study to Investigate TIVA With Propofol on Postoperative Pain and Side Effects

The University of Hong Kong (HKU)

Status: Withdrawn

Conditions: Postoperative Pain

Treatments: Drug: Propofol; Procedure: general anaesthesia

Study type: Observational

Funder types: Other

Identifiers

NCT03058354

UW17-001

Details and patient eligibility

About

Propofol is a commonly used anaesthetic with rapid recovery and less side effects and total intravenous anaesthesia (TIVA) with propofol is a common technique now. The reduction on certain serum pro- inflammatory cytokines may lead to more smooth post- surgical recovery.

Recent case report proved the analgesic effect of propofol infusion. However other animal and clinical studies showed controversial result.

The aim of this retrospective study is to investigate the postoperative analgesic effects and side effects of intraoperative TIVA with propofol in patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016.

Full description

Objectives:

1. To investigate the analgesic effects of propofol.
2. To evaluate the effect of propofol on postoperative adverse events.

Methods:

Retrospective audit.

Data Collection:

1. Demographic data;
2. Types of analgesic techniques;
3. Type of pain relief modalities;
4. Pain score up to 72 hours postoperatively;
5. Postoperative opioid consumption;
6. Incidence of adverse events during APS care;
7. Patients' satisfaction on pain relief.

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Anaesthetic records and acute pain service records of patient undergone surgery between 2014 to 2016 in Queen Mary Hospital would be retrieved from the computer.

Exclusion criteria

• Essential data were missing.
• Patient participating in other research projects.
• Changes in postoperative pain management technique.
• Patients could not be assessed post-operatively for pain (i.e. post-operative IPPV)

Trial design

0 participants in 2 patient groups

Group TIVA

Description:

Patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016 using intraoperative TIVA with propofol.

Treatment:

Drug: Propofol

Group GA

Description:

Patient undergoing surgery at Queen Mary Hospital, Hong Kong between 2014 to 2016 using general anaesthesia methods other than intraoperative TIVA with propofol.

Treatment:

Procedure: general anaesthesia