Study Trial of Dexamethasone Use for Alleviation of Symptoms After Scleral Buckle Eye Surgery

University of Toronto

Status and phase

Withdrawn

Phase 4

Conditions

Retinal Detachment

Treatments

Drug: Dexamethasone Sodium Phosphate Injection

Drug: Saline Injection

Study type

Interventional

Funder types

Other

Identifiers

NCT01326585

0911-A

Details and patient eligibility

About

Dexamethasone is a medication that has been shown to have clear anti-nausea, anti-inflammatory, and painkilling properties. Dexamethasone is currently used to manage postoperative symptoms of a variety of surgical procedures. However, its effect has not been validated for scleral buckling surgery, which is used to treat retinal detachment, a medical emergency that can lead to permanent blindness. In this study, the investigators will randomly administer dexamethasone to half of scleral buckling surgery patients, and a placebo to the other half. The investigators will then compare the postoperative symptoms of the two groups in order to determine whether dexamethasone should be used for scleral buckling surgeries.

Sex

All

Ages

18 to 79 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age 18-79 years old
Scheduled for scleral buckle surgery to treat a retinal detachment
Consent to participate in study

Exclusion criteria

Pregnant or nursing
Prior treatment with steroids
Severe diabetes mellitus (HbA1c > 8%)
Use of opioids, sedatives, or any kind of analgesics <1 week before scleral buckling surgery
History of alcohol or drug abuse