Studying a New Piece of Equipment That Can Help Plan Radiation Therapy of the Spine

Memorial Sloan Kettering Cancer Center (MSK)

Status: Active, not recruiting

Conditions: Thoracic Neoplasms; Spine Disease; Thoracic Diseases; Spine Metastases; Thoracic Cancer; Spine Cancer

Treatments: Diagnostic Test: MRI with custom MRI spine coil

Study type: Interventional

Funder types: Other

Identifiers

NCT04227717

19-476

Details and patient eligibility

About

Participants will receive an MRI with a custom-built MRI coil for each participant. The purpose is to find out whether this custom-built MRI coil can help doctors see the different parts of the spine as well as or better than they can with standard CT myelograms.

Enrollment: 9 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >/= 18 years of age at the time of treatment

• Able to give informed consent

• Consented for spine stereotactic radiation therapy

• No contraindications for CT myelograms which include:

  • Allergy to CT contrast
  • Use of phenothiazines
  • Platelet count < 60,000 K/mcl
  • INR > 1.5
  • VEGF inhibitor use in the past 2 weeks prior to myelogram
  • NSAID use in the past 5 days prior to myelogram
  • Renal disease
  • Creatinine > 1.2 mg/dL

• No contraindications for MRI scans which include:

  • Newly placed glucose monitors
  • Tattoos (Tattoos for radiation therapy are allowed)
  • Presence of a cardiac pacemaker
  • Presence of an implanted cardioverter defibrillator
  • Breast tissue expander
  • Aneurysm clip
  • Any other implanted metallic (BB, bullet, shrapnel, IUD, metallic stent or filter, spinal cord simulator etc.) or electronic device which is considered MR unsafe
  • Severe claustrophobia or inability to lie flat for the duration of the study, etc.

Exclusion criteria

• Presence of surgical spine hardware at the region of interest
• Presence of cervical spine lesions
• History of claustrophobia

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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9 participants in 1 patient group

Thoracic, lumbar and sacral spine lesions

Experimental group

Description:

Participants will have thoracic, lumbar and sacral spine lesions

Treatment:

Diagnostic Test: MRI with custom MRI spine coil