Studying Cognition in SPG4

University Hospital Tuebingen

Status: Completed

Conditions: Cognitive Impairment; Hereditary Spastic Paraplegia

Treatments: Diagnostic Test: CANTAB; Diagnostic Test: MOCA

Study type: Observational

Funder types: Other

Identifiers

NCT03104088

Cognition_SPG4

Details and patient eligibility

About

Comparing the cognitive levels of patients with SPG4 mutations to healthy controls.

Full description

Comparing the cognitive levels of patients with SPG4 mutations to healthy controls by using the CANTAB® and MoCA.

Enrollment: 50 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patient with SPG4 with known SPAST-Mutation (patient group) or healthy control
• Age 18 to 70 years
• Written, informed consent

Exclusion criteria

• Lack of ability for a written, informed consent
• Presence of gait disorder or other neurological condition (for healthy controls)

Trial design

50 participants in 2 patient groups

SPG4 patients

Treatment:

Diagnostic Test: CANTAB

Diagnostic Test: MOCA

Healthy controls

Treatment:

Diagnostic Test: CANTAB

Diagnostic Test: MOCA