Studying Pain and Symptom Distress in Patients With Advanced Colon Cancer, Rectal Cancer, Pancreatic Cancer, or Liver Cancer

City of Hope

Status: Completed

Conditions: Depression; Fatigue; Pain; Liver Cancer; Pancreatic Cancer; Colorectal Cancer

Treatments: Other: questionnaire administration; Other: medical chart review; Procedure: quality-of-life assessment; Other: study of socioeconomic and demographic variables

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT00950144

CDR0000632905 (Registry Identifier)

P30CA033572 (U.S. NIH Grant/Contract)

08131

CHNMC-08131

Details and patient eligibility

About

RATIONALE: Studying a patient's understanding of his or her illness, pain, symptoms, and quality-of-life may help the study of advanced cancer and may help patients live more comfortably.

PURPOSE: This clinical trial is studying pain and symptom distress in patients with advanced colon cancer, rectal cancer, pancreatic cancer, or liver cancer.

Full description

OBJECTIVES:

• To describe illness perception as indicated in the five domains of the Common Sense Model (i.e., identity, cause, time line, consequences, controllability) and their relationship to symptom distress in patients with colon, rectal, pancreatic, or liver (i.e., hepatocellular carcinoma) cancer.
• To describe pain and other symptoms and their relationship to overall symptom distress in these patients.
• To describe overall quality of life (QOL) and its specific summary scales in these patients.
• To explore the relationship among characteristics (i.e., sociodemographic, disease, health status) associated with illness perceptions, overall symptom distress, and QOL in these patients.

OUTLINE: Patients undergo an empirical examination of illness perceptions as predictors of disease, specifically from the five domains in the Common Sense Model. Patients undergo an assessment of the relationship between influencing characteristics (i.e., sociodemographic), symptoms, and behavioral factors (i.e., illness perceptions, overall symptom distress, and quality of life). Patients complete questionnaires to evaluate demographics by the Sociodemographic, Disease, and Health Status Tool; illness perception by the Illness Perception Questionnaire-Revised (IPQ-R); symptoms and symptom distress by the Memorial Symptom Assessment Scale (MSAS) and Brief Pain Inventory; and quality of life by the SF-12. Patients also undergo a medical chart review and self-report on sociodemographic characteristics.

Enrollment: 123 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

DISEASE CHARACTERISTICS:

• Histologically confirmed colon, rectal, pancreatic, or liver (i.e., hepatocellular carcinoma) cancer

  • Stage III or IV colon, rectal, or pancreatic cancer
  • Child-Pugh class B or C hepatocellular carcinoma

PATIENT CHARACTERISTICS:

• Able to read English
• Able to provide written informed consent and complete questionnaire packet

PRIOR CONCURRENT THERAPY:

• Any treatment modality (e.g., chemotherapy, radiotherapy, surgery) allowed