Studying the Association Between Folic Acid Deficiency and Social Isolation for Elderly Patients

University Hospital, Strasbourg, France

Status: Completed

Conditions: Folic Acid Deficiency; Elderly Patients; Social Isolation

Treatments: Other: Lubben Social Network Scale - 6

Study type: Observational

Funder types: Other

Identifiers

NCT04180800

7483

Details and patient eligibility

About

Social isolation among elderly people is a frequent and major determinant for health.

The risk of premature death is 2 to 5 time higher for socially isolated people, similarly for morbidity, duration of healing and complications rate.

Denutrition is also frequent for elderly people with potentially serious consequences. Vitamin deficiency, especially in B9 and B12 vitamins, are often associated with denutrition among elderly people.

Folic acid (vitamin B9) is not influenced by inflammation and folic acid income are necessarily exogene. Vitamin B9 is provided by fresh fruits and vegetables, and giblets.

The investigators observed a high prevalence in folic acid deficiency for socially isolated elderly patients. The investigators made the hypothesis that a folic acid defiency is associated with social isolation for elderly people.

The primary purpose is the study of the association between folic acid deficiency (measured by dosing of plasma concentration of vitamin B9) and social isolation evaluated by Lubben Social Network Scale in 6 questions.

The secondary purposes are the study of the correlation between folic acid deficiency and social conditions, nutritional status, biological data, poly pharmacy, cognitive functions, dependency and length of stay at hospital.

Enrollment: 61 patients

Sex: All

Ages: 75+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion criteria :

• Patients hospitalized in geriatric rehabilitation care in Strasbourg University Hospital
• Age > 75 years
• Patient has given his consent

Exclusion criteria :

• Digestive malabsorption disorder : gastrectomy, extended intestinal resection, Crohn disease, celiac disease, parenteral nutrition
• Chronic alcoholism
• Treatment with sulfamids, methotrexate, anti epileptic treatment (hydantoin)
• Hemodialysis
• Patients under protection measure (curatorship, guardianship, judicial protection)
• Patient refuses to participate

Trial design

61 participants in 2 patient groups

Folic acid deficiency

Description:

Those with a folic acid defiency

Treatment:

Other: Lubben Social Network Scale - 6

No deficiency

Description:

Those with no folic acid deficiency

Treatment:

Other: Lubben Social Network Scale - 6