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STUMBL vs TTSS in Predicting Morbidity and Mortality of Blunt Chest Trauma

A

Assiut University

Status

Not yet enrolling

Conditions

Blunt Chest Wall Trauma

Treatments

Diagnostic Test: Chest X-Ray
Diagnostic Test: Computed Tomography (CT) Chest (with or without contrast)

Study type

Observational

Funder types

Other

Identifiers

NCT07270354
STUMBL-TTSS-BluntChestTrauma

Details and patient eligibility

About

This study aim to compare the effectiveness of the STUMBL Score and the Thoracic Trauma Severity Score (TTSS) in predicting morbidity and mortality in patients with blunt chest wall trauma, and to evaluate which scoring system provides greater clinical utility for early risk stratification and management decisions.

Full description

Blunt chest wall trauma poses a clinical challenge due to its substantial contribution to morbidity and mortality, particularly following falls and vehicular accidents. Early identification of patients at high risk of complications is critical yet difficult, as delayed respiratory issues often escape initial detection. Traditional trauma scoring systems (e.g. ISS, AIS) lack specificity for isolated thoracic injury, creating a niche for more focused prognostic tools.

Two promising models have emerged: the STUMBL Score-based on age, number of rib fractures, chronic lung disease, pre-injury anticoagulant use, and oxygen saturation-is explicitly designed for blunt chest trauma prognosis. Studies report strong discriminatory performance, with development-phase c-index up to 0.96 . External validations vary: one UK cohort showed STUMBL ≥ 11 had a sensitivity of 79%, specificity of 78%, and AUC of 0.84-comparable to clinician judgment ; Italian data demonstrated excellent discrimination (C-index ~0.90) and calibration .

The Thoracic Trauma Severity Score (TTSS), initially validated in polytrauma ICU patients, yields moderate to good discrimination (c-indices 0.72-0.85) across validation studies .

Though these scores show promise, high methodological bias and limited external validations temper their widespread adoption . A direct, comparative analysis of STUMBL and TTSS within a well-defined patient cohort is thus needed.

Enrollment

124 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Adult patients (≥18 years) presenting with blunt chest trauma.
  • Patients who have given written informed consent to participate in the study

Exclusion criteria

  • Penetrating chest injuries
  • Pediatric patients (<18 years)
  • Patients with incomplete records or who decline consent
  • Pregnant women
  • Disturbed conscious patients
  • Mechanically ventilated patients
  • Polytrauma patients

Trial design

124 participants in 1 patient group

Blunt Chest Trauma group
Description:
The Blunt Chest Trauma Cohort comprises all consecutive adult patients (≥18 years) presenting with blunt chest trauma to the Emergency Department of Assiut university between October 2025 and October 2026. Patients meeting inclusion criteria will be enrolled prospectively and followed throughout their hospital stay to record clinical course and outcomes. At presentation both the STUMBL and TTSS scores will be calculated for each patient using standard definitions. The cohort will be analyzed as a single group to evaluate the predictive performance of each score for predefined outcomes (morbidity and mortality)
Treatment:
Diagnostic Test: Computed Tomography (CT) Chest (with or without contrast)
Diagnostic Test: Chest X-Ray

Trial contacts and locations

0

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Central trial contact

Mohamed Emad Ahmed Swefy, M.B.B.Ch

Data sourced from clinicaltrials.gov

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