Subcision Followed by Diluted Calcium Hydroxylapatite Injection Versus Subcision Followed by Painting CROSS TCA Technique for the Treatment of Atrophic Acne Scars

Tanta University

Status

Completed

Conditions

Calcium Hydroxylapatite

Trichloroacetic Acid

Atrophic Acne Scar

Subcision

Treatments

Drug: Painting chemical reconstruction of skin scars trichloroacetic acid technique

Drug: Calcium hydroxylapatite filler

Study type

Interventional

Funder types

Other

Identifiers

NCT07028567

36195/12/22

Details and patient eligibility

About

This study aimed to compare the safety and efficacy of subcision followed by diluted calcium hydroxyapatite injection versus subcision followed by the painting original chemical reconstruction of skin scars (CROSS) technique using trichloroacetic acid (TCA) for the treatment of atrophic acne scars.

Full description

Atrophic scars present as depressions secondary to fibrous contractions. Subcision is a technique in which a needle is inserted under the acne scar to sever the fibrous tissue (tethers) that bind down the scar. This releases the fibrous tissue.

The original chemical reconstruction of skin scars (CROSS) technique using trichloroacetic acid (TCA) entails focal application of highly concentrated TCA (70% to 100%) with firm pressure applied to the entire atrophic area using a sharpened wooden applicator until frosting occurs.

Fillers containing hyaluronic acid, calcium hydroxyapatite, and poly-L-lactic acid are increasingly used to correct atrophic acne scarring as they augment soft tissue in variable degree and are most effective in soft rolling or boxcar scars.

Enrollment

13 patients

Sex

All

Ages

20 to 50 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Age from 20 to 50 years.
Both sexes.
Patients with atrophic acne scars.

Exclusion criteria

Patients with Fitzpatrick skin phototypes V and VI.
Receiving systemic isotretinoin medication at the time of the study.
Active bacterial, viral or fungal infections in the treatment area.
Hypertrophic scarring or keloidal tendency.
Photosensitivity or photodermatitis.
Unrealistic expectation, bleeding, coagulation disorders, and any other related skin disease.
Pregnant or lactating females.
Chronic debilitating diseases such as diabetes mellitus, cardiovascular diseases, renal failure, hepatic diseases, chronic respiratory diseases or any endocrine diseases.
History of immunosuppressive drug intake or chemotherapy within 6 months before treatment.