Subfoveal Choroidal Thickness in Thai Population

Khon Kaen University

Status: Terminated

Conditions: Healthy

Treatments: Other: measure subfoveal choroidal thickness

Study type: Observational

Funder types: Other

Identifiers

NCT02551601

HE561056

Details and patient eligibility

About

The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using spectral-domain optical coherence tomography with enhanced depth imaging technique.

Full description

Alteration of choroidal blood supply causes changes in choroidal thickness and results in choroidal abnormalities. These are usually associated with retinal diseases and leading to severe visual dysfunction. Choroidal thickness is therefore helpful in diagnosis and treatment for many chorioretinal conditions. With the advent of spectral domain optical coherence tomography and enhanced depth imaging technique, choroidal thickness has been investigated widely in normal eyes and various chorioretinal diseases including central serous chorioretinopathy (CSC), age-related macular degeneration (AMD), highly myopia and Vogt Koyanagi-Harada disease. Similar to retinal thickness, a normal baseline choroidal thickness might be used for interpretation. This value might be affected by several variables including age, gender and ethnicity. Although there were previous studies on subfoveal choroidal thickness in normal eyes from many countries, there has been no such study in Thailand. The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using SD-OCT and EDI technique.

Enrollment: 150 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age 18 years or above
• Healthy subjects
• No ocular diseases
• Written informed consent form

Exclusion criteria

• patients with systemic diseases that may affect retinal or choroidal thickness including diabetes
• patients with history of refractive surgeries, intraocular surgeries or retinal laser treatments
• patients with history of macular, retinal, or optic nerve abnormalities

Trial design

150 participants in 1 patient group

Healthy volunteers

Description:

to measure the subfoveal choroidal thickness in healthy volunteers

Treatment:

Other: measure subfoveal choroidal thickness