Subjects With T2D or at Risk of T2D Cohort Follow-up (DESCENDANCE)

Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète

Status: Active, not recruiting

Conditions: Diabetes Mellitus, Type 2

Treatments: Other: HbA1c; Diagnostic Test: OGTT; Other: Questionnaire

Study type: Observational

Funder types: Other

Identifiers

NCT05567692

2022-A01538-35

Details and patient eligibility

About

The main objective of this study is to prospectively follow the subjects included in "Descendance" cohort and to describe the occurrence of type 2 diabetes in non-diabetic subjects, which will allow us to iteratively update the "Descendance" Type 2 Diabetes risk prediction model.

Full description

High risk families will be prospectively follow in order to better understand the risk of transmission of type 2 diabetes from one generation to another. The cohort will also allow us to collect additional data on diabetic patients.

The monitoring of the cohort will take place for at least 10 years with a follow-up of all participants every three years. To detect individuals who develop dysglycemia during the study, a glucose tolerance test (GTT) and HbA1c measurement will be conducted.

Enrollment: 837 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects have participated in the Descendance study
• Subjets who sign informed consent to participate in the study

Exclusion criteria

• Subjects not enrolled in Descendance study
• Subjects refusing to participate
• Pregnant or breastfeeding
• Subjects in emergency situations, under legal protection or unable to provide informed -consent
• Subjects lost to follow-up or died

Trial design

837 participants in 2 patient groups

T2D group

Description:

subjects with type 2 diabetes

Treatment:

Other: Questionnaire

Non-T2D group

Description:

healthy subjects

Treatment:

Other: Questionnaire

Diagnostic Test: OGTT

Other: HbA1c