Substance Dependent Teens - Impact of Treating Depression Study 1 - 1
Status and phase
Conditions
Treatments
Details and patient eligibility
About
The purpose of this study is to evaluate the impact of treating depression on substance dependent teens.
Full description
The primary study aim is to determine whether fluoxetine + CBT is a more effective treatment than placebo + CBT for substance outcomes, depression, and behavior problems. The current community standard of care often withholds pharmacotherapy for depression in substance abusing adolescents, since it is often assumed that their depressions may remit with SUD treatment alone. However, this is an untested hypothesis in adolescents and one that we propose to test in the current study.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Must have DSM IV non bipolar Major Depressive disorder (by clinical interview), DSM IV Conduct Disorder, and Non-Tobacco Substance Disorder.
Exclusion criteria
- History of or current psychosis, history of psychotic depression, bipolar disorder I or II, family history of first degree relative with bipolar I, lifetime history of non-substance induced Mania/Hypomania
- Unstable chronic or serious medical illness
- Currently pregnant
- Take psychotrophic medication, past 2 months: medication or treatment for depression, clinically significant laboratory abnormality
Trial design
Primary purpose
Allocation
Interventional model
Masking
126 participants in 2 patient groups, including a placebo group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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