Subtenon Block Combined With General Anesthesia for Vitreoretinal Surgery

King Saud University

Status and phase: Completed; Phase 3

Conditions: Subtenon Anesthesia

Treatments: Drug: 2% lidocaine and 0.5% bupivacaine; Drug: Sham subtenon block

Study type: Interventional

Funder types: Other

Identifiers

NCT02282774

E-13-968

Details and patient eligibility

About

To evaluate the effects of subtenon block (SB) as an adjunct to general anaesthesia on postoperative pain, oculocardiac reflex and postoperative nausea and vomiting for vitreoretinal surgery.

Enrollment: 80 patients

Sex: All

Ages: 40 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient undergoing elective retinal surgery under general anesthesia

Exclusion criteria

• ASA physical status > Grade II,
• psychiatric conditions,
• neurological impairment,
• deafness with whom communication would be difficult in the postoperative period,
• clotting abnormalities,
• contraindications for regional anesthesia,
• drug abuse,
• history of allergy to the study drugs,
• previous vitreoretinal or strabismus surgery,
• endophthalmitis, or inflammatory eye pathology
• taking analgesics, antiemetics or drugs that might affect hemodynamics

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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80 participants in 2 patient groups

SB

Experimental group

Description:

receive subtenon block of 4mL of 2% lidocaine and 0.5% bupivacaine (50:50) mixture

Treatment:

Drug: 2% lidocaine and 0.5% bupivacaine

C

Sham Comparator group

Description:

receive subtenon block of 4mL saline

Treatment:

Drug: Sham subtenon block