Success of Endodontic Treatment With Different Obturation Techniques and Sealer Cements

University of Siena

Status: Enrolling

Conditions: Pulpitis; Periapical Periodontitis; Periapical Lesions; Periapical Pathology

Treatments: Procedure: AH Plus (Dentsply Sirona, Charlotte, NC, USA); Procedure: Continuous Wave Condensation; Procedure: Single Cone Technique; Procedure: NeoSealer Flo

Study type: Interventional

Funder types: Other

Identifiers

NCT07019298

HCCWC001

Details and patient eligibility

About

The present study aims to compare the radiographic success of endodontic treatment using Orstavik's criteria between two sealers: AH Plus (Dentsply DeTrey, Konstanz, Germany) and Neosealer Flo (Avalon Biomed, Bradenton, Florida, USA), as well as between two obturation techniques: continuous wave and single cone. The study includes 270 patients, with a minimum follow-up period of 6 months. Clinical and radiographic variables will be assessed, including quality of obturation, lesion healing, and restoration. The study seeks to determine if the use of bioceramic sealer is effective regardless of the obturation technique used, highlighting the importance of clinical follow-up to evaluate endodontic treatment success.

Enrollment: 270 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

Patients aged 18 years and older. Teeth with a diagnosis of pulpal necrosis or irreversible pulpitis. Informed consent provided for data usage.

Exclusion criteria

• Patients with systemic conditions that may impair healing (e.g., uncontrolled diabetes, immunosuppression).
• Teeth with root fractures, resorption, or open apices.
• Incomplete clinical or radiographic records.
• Cases with poor-quality radiographs or lack of standardization for evaluation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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270 participants in 4 patient groups

AH Plus + Continuous Wave Condensation

Active Comparator group

Description:

Root canal obturation using AH Plus (Dentsply Sirona, Charlotte, NC, USA) and the continuous wave technique with thermoplasticized gutta-percha

Treatment:

Procedure: Continuous Wave Condensation

Procedure: AH Plus (Dentsply Sirona, Charlotte, NC, USA)

AH Plus + Single Cone

Active Comparator group

Description:

Root canal obturation using AH Plus and the single cone technique with cold gutta-percha.

Treatment:

Procedure: Single Cone Technique

Procedure: AH Plus (Dentsply Sirona, Charlotte, NC, USA)

NeoSealer Flo + Continuous Wave

Experimental group

Description:

Root canal obturation using NeoSealer Flo (Avalon Biomed, Houston, TX, USA) and the continuous wave technique.

Treatment:

Procedure: NeoSealer Flo

Procedure: Continuous Wave Condensation

NeoSealer Flo + Single Cone

Experimental group

Description:

Root canal obturation using NeoSealer Flo and the single cone technique.

Treatment:

Procedure: NeoSealer Flo

Procedure: Single Cone Technique