Successful Aging and Age-related Decline (MyAgeWell)

Sunway University

Status: Enrolling

Conditions: Aging; Cognitive Decline; Intervention Study; Elderly; Physical Decline

Treatments: Behavioral: Physical activity; Behavioral: Cognitive stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT06376656

LRGS/1/2019/SYUC/02/1

Details and patient eligibility

About

Recent studies have shown promising cognitive and physical interventions aimed at slowing down ageing-related declines in quality of life, but they lack strong ecological validity (brief durations, unrealistic goals, no real-world application) and has yet to show robust evidence that such interventions are stable and suitable in the long-term. The investigators aim to examine whether these interventions can, over four years, significantly slow down the normal rate of ageing-related decline.

Full description

This is a longitudinal, controlled, cohort study. The overarching aim in this intervention study is three-fold: (1) to test hypotheses derived from ageing-related theories, (2) to provide robust measurable evidence both in the long-term and validate meaningful interventions, and (3) provide quantifiable cost-benefit ratio to suggested solutions. A cohort of Malaysian older adults will be recruited and assigned to one of the groups, either cognitive stimulation, physical activity, combined cognitive stimulation and physical activity, or non-intervention control.

Enrollment: 400 estimated patients

Sex: All

Ages: 60+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Malaysian older adults aged 60 and above who fulfil the following criteria will be recruited:

Inclusion Criteria:

• Healthy and this includes those seeking regular medical attention,
• Have some form of mobility (ability to walk short distances at least 3m),
• Able to communicate in at least one of the following languages: English, Malay, Mandarin, Tamil.

Exclusion Criteria:

• Older adults with a history of stroke,
• Diagnosis of neurodegenerative diseases (such as Alzheimer's disease or Parkinson's) or psychiatric disorders,
• Uncorrected auditory and/or visual impairments,
• Currently on psychiatric medications,
• Immobile,
• Require full-time caregiver assistance,
• With comprehension impediments from the assessment portion of this project,
• A Montreal Cognitive Assessment (MoCA) score of <13.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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400 participants in 4 patient groups

Cognitive stimulation

Experimental group

Description:

Participants will take part in psychoeducation, videogaming, book club and technology training workshops.

Treatment:

Behavioral: Cognitive stimulation

Physical activity

Experimental group

Description:

Participants will take part in walking, Zumba, resistance exercise and aerobics sessions.

Treatment:

Behavioral: Physical activity

Combined intervention

Experimental group

Description:

Participants will take part in both cognitive stimulation and physical activity intervention sessions.

Treatment:

Behavioral: Cognitive stimulation

Behavioral: Physical activity

Non-intervention control

No Intervention group

Description:

Participants will not take part in any intervention.