Succinylcholine or Rocuronium for Rigid Bronchoscopy Under General Anesthesia (Broncho-SR)

Hopital Foch

Status and phase: Terminated; Phase 4

Conditions: Anesthesia

Treatments: Drug: rocuronium; Drug: succinylcholine

Study type: Interventional

Funder types: Other

Identifiers

NCT01579864

2011-000370-59 (EudraCT Number)

2011/05

Details and patient eligibility

About

Myorelaxation is generally used as a part of general anesthesia for interventional rigid bronchoscopy. Succinylcholine is most often used because its short duration of action but rocuronium can be used since sugammadex permits a rapid and complete reversal of the neuromuscular block. The aim of ths study is to compare both agents.

Enrollment: 6 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients scheduled for an interventional rigid bronchoscopy under general anesthesia

Exclusion criteria

• pregnant woman or woman of childbearing age,
• morbid obesity,
• drug allergy,contra-indication to succinylcholine, rocuronium, sugammadex, propofol, remifentanil,
• history of central neurological or brain damage,
• psychotropic treatment,
• pacemaker,
• renal failure,
• disease of the neuromuscular junction.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

6 participants in 2 patient groups

succinylcholine

Active Comparator group

Description:

Succinylcholine 1 mg/kg and a second dose if necessary.

Treatment:

Drug: succinylcholine

Rocuronium

Experimental group

Description:

rocuronium 0,9 mg/kg with additional boluses of 0,3 mg/kg f necessary

Treatment:

Drug: rocuronium