Sugammadex and Time to Extubation in Ophthalmic Surgery

China Medical University

Status

Completed

Conditions

Sugammadex

Extubation Readiness

Ophthalmologic Surgical Procedure

Neostigmine

General Anesthesia Using Endotracheal Intubation

Treatments

Drug: sugammadex

Drug: Neostigmine + Atropine

Study type

Observational

Funder types

Other

Identifiers

NCT06632067

CMUH112-REC3-124

Details and patient eligibility

About

This study is to invastigate if patients treated with sugammadex compared to neostigmine/atropine would be extubate faster upon emergence of anesthesia.

Full description

This is a retrospective case-control study including patients aged 18 years or older who underwent ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022. Patients who received rocuronium as the sole neuromuscular blocking agent and were maintained with sevoflurane or desflurane and intravenous fentanyl were included. Based on the choice of reversal agent for neuromuscular blockade, patients were divided into two groups: the sugammadex group or the neostigmine group. Patients who underwent emergency surgery or combined surgeries with other specialties were excluded. Patient characteristics, including age, gender, ASA classification, weight, and height, were collected. Anesthesia-related medications were recorded. The time points of anesthesia induction, start and end of surgery, reversal agent administration, and tracheal extubation were documented.

Enrollment

262 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

aged 18 years or older ophthalmic surgeries under general anesthesia with tracheal intubation between 2020 and 2022 received rocuronium as the sole neuromuscular blocking agent maintained with sevoflurane or desflurane and intravenous fentanyl

Exclusion criteria

emergency surgery combined surgeries with other specialties