Suicide Prevention Intervention for Schizophrenia-Spectrum Disorders (CLASP-S)

Butler Hospital

Status: Completed

Conditions: Schizophrenia; Suicide

Treatments: Behavioral: Coping Long-term with Active Suicide Program for Schizophrenia; Behavioral: Enhanced Treatment as Usual

Study type: Interventional

Funder types: Other

Identifiers

NCT04221269

1908-001

Details and patient eligibility

About

The current project is a pilot randomized controlled trial to test the Coping Long-term with Active Suicide Program for schizophrenia-spectrum disorders (CLASP-S) for patients following a psychiatric hospitalization. Participants will be assigned to enhanced treatment as usual (ETAU) alone vs CLASP-S plus ETAU. Participants complete assessments at baseline during their psychiatric hospitalization and at 3 months (mid-treatment) and 6 months (post-treatment) following discharge. The primary aim is to assess the feasibility and acceptability of CLASP-S. The secondary aim is to estimate the effects of CLASP-S on reducing suicidal thoughts and behaviors relative to ETAU.

Enrollment: 30 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• suicidal thoughts or behaviors prior to hospital admission
• diagnosis of a schizophrenia-spectrum disorder
• receiving pharmacotherapy
• 18 years or older
• speaks/reads English

Exclusion criteria

• psychosis due to substance use or medical condition
• lack of phone access
• discharge to long-term facility

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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30 participants in 2 patient groups

Enhanced Treatment as Usual

Active Comparator group

Description:

Participants assigned to Enhanced Treatment as Usual (ETAU) alone will receive unrestricted routine care in the community. Assessment feedback reports will be sent to participants' community providers at baseline, 3 months, and 6 months for care coordination.

Treatment:

Behavioral: Enhanced Treatment as Usual

Coping Long-term with Active Suicide Program for Schizophrenia

Experimental group

Description:

Coping Long-term with Active Suicide Program for Schizophrenia-Spectrum Disorders (CLASP-S) includes 3 individual sessions, 1 family meeting, and 11 phone sessions with the participant and their significant other over 6 months post-hospital discharge.

Treatment:

Behavioral: Coping Long-term with Active Suicide Program for Schizophrenia

Behavioral: Enhanced Treatment as Usual