Sunscreen: Persistence of Sun Protection Factor and the Influence on Vitamin D (sunscreen)

Bispebjerg Hospital

Status: Unknown

Conditions: Sunscreen Persistence; Vitamin D Production in the Skin

Treatments: Radiation: UVB light; Other: sunscreen MATAS sunlotion SPF 8

Study type: Interventional

Funder types: Other

Identifiers

NCT00711256

H-B-2007-120

Details and patient eligibility

About

The investigators want to investigate whether sunscreen is removed by clothing and to what extend when the amount of sunscreen applied varies.Does clothing reduce the SPF when clothes are put on 20, 8, or 4 minutes after sunscreen application? The investigators also want to investigate the persistence of sunscreen during eight hours indoor. How much does the SPF reduces? Furthermore, we want to investigate whether sunscreen in the layers 2, 1, and 0.5 mg/cm2 reduce the vitamin D production in the skin.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy participants.
• > 18 years.
• Skin type I, II, and III.

Exclusion criteria

• Pregnancy.
• Medicin use.
• Skin or other diseases.
• The participants must not have been in solarium or gotten sun on their trunks in the 3 months before the study start and during the study.
• Skin types IV and above.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Factorial Assignment

Masking: None (Open label)

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80 participants in 4 patient groups

1

Active Comparator group

Description:

No sunscreen applied

Treatment:

Radiation: UVB light

2

Active Comparator group

Description:

Sunscreen applied 0.5 mg/cm2

Treatment:

Radiation: UVB light

3

Active Comparator group

Description:

Sunscreen applied 1mg/cm2

Treatment:

Radiation: UVB light

4

Active Comparator group

Description:

Sunscreen applied 2mg/cm2

Treatment:

Other: sunscreen MATAS sunlotion SPF 8

Radiation: UVB light