Superficial Cryotherapy Versus Microneedling in Alopecia Areata

Sohag University

Status

Completed

Conditions

Alopecia Areata

Treatments

Procedure: DMEP kit

Device: Dermapen

Study type

Interventional

Funder types

Other

Identifiers

NCT04680234

Alopecia2020

Details and patient eligibility

About

This study is randomized comparative analytical prospective study that included patients with mild and moderate alopecia areata. Patients was divided into two groups Patients in the first group underwent Superficial cryotherapy using dimethyl ether and propane (DMEP) at -57C (Cryotherapy group). Patients in the second group underwent Microneedling (Microneedling group). A total of six sessions were done at 2 weeks interval. Patients were followed-up for next 3 months to evaluate the persistence of hair regrowth after therapy. Patients were assessed at baseline and during follow up using photography, Dermoscopy, SALT score and regrowth scale.

Enrollment

100 patients

Sex

All

Ages

4+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

ِAlopecia areata patients

Exclusion criteria

Alopecia totalis and universalis
ِAge less than four years.
ِPregnancy or breast-feeding.
ِActive infection at the site alopecia patch(s).
ِInflammation ate site of the alopecia patches
ِIntolerance to cold.
ِAssociated systemic illness such as thyroid, pernicious anaemia, diabetes mellitus, autoimmune connective tissue diseases.
ِPrevious treatment for alopecia areata over the last three months.