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Superior Vena Caval Obstruction (SVCO) - Management and Outcome

University Health Network, Toronto logo

University Health Network, Toronto

Status and phase

Completed
Phase 2
Phase 1

Conditions

Superior Vena Cava Syndrome

Treatments

Behavioral: Management and Outcome of SVCO

Study type

Interventional

Funder types

Other

Identifiers

NCT00259584
UHN REB 01-0770-C

Details and patient eligibility

About

All patients with symptomatic malignant SVCO deemed suitable for treatment either with radiation therapy or by stenting will be eligible. They will receive whichever treatment is deemed most clinically appropriate. Symptomatic response, time to onset of palliation, duration of symptom control and survival will be assessed.

Enrollment

20 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria:

  • Symptomatic clinical and radiological diagnosis of superior vena caval obstruction.
  • Underlying histological diagnosis deemed appropriate for palliative radiotherapy as treatment by investigator. Patients with chemosensitive tumours such as small cell lung cancer (both untreated and recurrent), lymphoma and testicular tumours, will be eligible if radiation is deemed to be appropriate treatment.

Trial design

Primary purpose

Treatment

Allocation

Non-Randomized

Interventional model

Single Group Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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