Supernormal Goal for Proximal Femur Fracture

Guangzhou First People's Hospital

Status: Unknown

Conditions: Femoral Fractures

Treatments: Procedure: Supernormal oxygen delivery goal therapy

Study type: Observational

Funder types: Other

Identifiers

NCT02194101

GZFPH-IRB-2013-049

Details and patient eligibility

About

This is an observational pilot study of supernormal oxygen delivery goal for patients with proximal femoral fracture.

Full description

Augmentation of oxygen delivery using fluids with or without inotropes has been shown to improve surgical outcome in high-risk patients. Patients with proximal femoral fracture are considered high risk. However, most of this cohort elderly patients have poor cardiovascular condition and may not achieve the oxygen delivery goal. We will perform an observational pilot study whether the supernormal oxygen delivery is a valid hemodynamic goal for patients with proximal femoral fracture.

Enrollment: 30 estimated patients

Sex: All

Ages: 70+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged over 70 yr
• Weight over 35 kg
• Underwent proximal femur fracture (PFF) surgery under peripheral nerve block and laryngeal mask airway anesthesia.

Exclusion criteria

• Patients who could be harmed due to the treatment (ongoing myocardial infarction, chronic dialysis)
• Monoamine oxidase inhibitor use within the last 14 days
• Pathological fractures and conditions
• Inability to give informed consent(as judged by a research team member)
• Anticipated difficulties obtaining data during the first postoperative year (as judged by a research team member)

Trial design

30 participants in 1 patient group

Supernormal oxygen delivery goal therapy

Description:

Patients will be aged over 70 yr and weight over 35 kg, and undergoing proximal femur fracture (PFF) surgery under peripheral nerve block and laryngeal mask airway anesthesia.

Treatment:

Procedure: Supernormal oxygen delivery goal therapy