Supervised Endurance Training Among Pulmonary Arterial Hypertension Patients

Riphah International University

Status

Completed

Conditions

Pulmonary Arterial Hypertension

Treatments

Other: Supervised endurance exercise training + Patient Education

Other: Home exercises + Patient Education

Study type

Interventional

Funder types

Other

Identifiers

NCT05947032

REC/01603 Farheen Khan

Details and patient eligibility

About

To compare the effects of supervised endurance training versus home based exercise plan on functional capacity and fatigue among pulmonary arterial hypertension patients.

Enrollment

50 patients

Sex

All

Ages

20 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Patients with pulmonary arterial hypertension, not pregnant and tobacco free.
Age = 21 to 82
Patients with documented PAH diagnosed by echocardiography (enlarged RA an enlarged RV with a thick wall, septal shift by enlarged chambers of right side of heart, an elevated mPAP) or a resting mean pulmonary arterial pressure equal to 25mm Hg determined by right heart catheterization.
Patients on stable PH therapies, sedentary, and had no pulmonary rehabilitation for 6 months prior to enrolment.

Exclusion criteria

Patients will be excluded if they are not able to complete 6MWT.
A documented pulmonary capillary wedge pressure greater then or equal to 15 mm Hg.
Significant hepatic, renal, metabolic or mitochondrial dysfunctions; severe psychiatric disease; use of beta-adrenergic blockers or antiretroviral therapies; and any musculoskeletal or neurological condition that would limit walking or exercise performance.
Patients with a history of heart failure.