Supplement Intake in Infertile Men;the Effect on Sperm Parameters,Fertilization Rate and Embryo Quality

Hillel Yaffe Medical Center

Status: Unknown

Conditions: Oligospermia

Treatments: Dietary Supplement: Vitamale

Study type: Interventional

Funder types: Other

Identifiers

NCT01520584

0103-10

Details and patient eligibility

About

The vitamin,minerals and amino acid supplementation for 3 months will improve the semen parameters,fertilization rate and embryo quality in subfertile men undergoing IVF treatment

Full description

With the supplement intake containing amino acids, vitamins and minerals designed to improve sperm parameters, the couples undergoing IVF treatment will benefit as the change and improvement of sperm parameters will increase the fertilization rate and improve the embryo quality thus allowing shorter time for pregnancy achievement and less frustration with long duration of treatments

Enrollment: 40 estimated patients

Sex: Male

Ages: 20 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• healthy male age 20-50
• at least one IVF cycle without pregnancy
• sperm parameters:
• Oligospermia 5-20*106
• Teratospermia 6-14% normal forms
• Asthenospermia <30% motility

Exclusion criteria

• female factor infertility
• age > 50 or under 20
• testicular problem on physical examination
• history of malignancy and /or chemotherapy
• usage of antiandrogen/testosterone
• history of drug abuse/alcohol
• a known endocrinological problem
• current STD or genitourinary infection
• Retrograde Ejaculation
• Y chromosome microdeletion
• Karyotype abnormalities

Trial design

40 participants in 2 patient groups, including a placebo group

vitamale

Active Comparator group

Treatment:

Dietary Supplement: Vitamale

sham pill

Placebo Comparator group

Treatment:

Dietary Supplement: Vitamale