Supplemental Perioperative Oxygen to Reduce the Incidence of Post-Cesarean Endometritis and Wound Infection

University of Washington

Status: Completed

Conditions: Wound Infection or Endometritis Post Cesarean Section

Treatments: Procedure: supplemental perioperative oxygen

Study type: Interventional

Funder types: Other

Identifiers

NCT00670020

18821

Details and patient eligibility

About

The purpose of this study is to determine whether supplemental perioperative oxygen significantly decreases the incidence of post-Cesarean endometritis and wound infection among women who undergo Cesarean section after the onset of labor.

Full description

Women undergoing cesarean section after rupture of membranes or onset of labor are randomized in a one to one ratio to either normal or supplemental perioperative oxygen during cesarean section and for two hours afterwards.

Enrollment: 143 patients

Sex: Female

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Women who underwent a clinically indicated cesarean delivery after the onset of labor or rupture of membranes

Exclusion criteria

• Cesarean delivery prior to the onset of labor or rupture of membranes
• emergent cesarean delivery
• general endotracheal anesthesia
• clinical chorioamnionitis
• HIV infection
• less than 16 years of age

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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143 participants in 2 patient groups

1

Experimental group

Description:

supplemental perioperative oxygen

Treatment:

Procedure: supplemental perioperative oxygen

2

No Intervention group

Description:

Normal