Supplementary Oxygen in Surgical and Medical Wards Evaluated by 30-day Mortality (SOSAM)

H

Hannibal Troensegaard

Status

Completed

Conditions

Oxygen Deficiency
Oxygen Toxicity

Treatments

Drug: Oxygen gas

Study type

Observational

Funder types

Other

Identifiers

NCT03625700
OxyEWS2018

Details and patient eligibility

About

This study evaluates the use and effects of supplementary oxygen in surgical and medical wards on patients admitted to a hospital in the capital region of Denmark. The population will be divided in to three groups according to their oxygenation status. The main outcome will be 30-day mortality, with secondary outcomes being Length of stay, 30-day admission to ICU, 30-day reoperations, 30-day readmission, and peak values within 30-days of C-reactive protein, S-Creatinine, Troponin.

Enrollment

11,196 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Admission date between 1st of January 2014 to 29th of December 2014 on a hospital in the capital region of Denmark
  • Age ≥18

Unique (first) admission in database for either:

  • Hip fracture requiring surgery
  • Chronic obstructive pulmonary disease in exacerbation
  • Acute mycardial infarction
  • Open abdominal surgery

Exclusion criteria

  • No data on saturation within 48 hours after
  • Admission (Medical patients)
  • Discharge from the post anaesthesia care unit (Surgical patients)
  • No data on primary outcome (30-day mortality)

Trial design

11,196 participants in 3 patient groups

Hypoxia
Description:
Patients without chronic obstructive pulmonary disease: blood oxygen saturation <94 % irrespective of supplemental oxygen Patients with chronic obstructive pulmonary disease: blood oxygen saturation <88% irrespective of supplemental oxygen
Treatment:
Drug: Oxygen gas
Normoxia
Description:
Patients without chronic obstructive pulmonary disease: blood oxygen saturation 94-98% in combination with supplemental oxygen OR blood oxygen saturation ≥94% without supplemental oxygen. Patients with chronic obstructive pulmonary disease: blood oxygen saturation 88-92% in combination with supplemental oxygen OR blood oxygen saturation ≥88% without supplemental oxygen.
Treatment:
Drug: Oxygen gas
Hyperoxia
Description:
Patients without chronic obstructive pulmonary disease: blood oxygen saturation >98% in combination with supplemental oxygen Patients with chronic obstructive pulmonary disease: blood oxygen saturation >92% in combination with supplemental oxygen
Treatment:
Drug: Oxygen gas

Trial documents
1

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2024 Veeva Systems