Supplementation of Vitamin D in Patients With Type 2 Diabetes and Hypertension

Hospital de Clinicas de Porto Alegre

Status: Terminated

Conditions: Hypertension

Treatments: Dietary Supplement: supplementation of 100.000 IU of vitamin D3; Dietary Supplement: placebo pill

Study type: Interventional

Funder types: Other

Identifiers

NCT02204527

140415

Details and patient eligibility

About

In patients with type 2 diabetes, the effects on blood pressure of vitamin D has been shown to be variable. Thus, the goal of this proposal is to evaluate the effect of vitamin D supplementation in patients with type 2 diabetes and hypertension

Enrollment: 40 patients

Sex: All

Ages: 30 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• type 2 diabetes
• hypovitaminosis D
• hypertension

Exclusion criteria

• pregnant or lactating
• patients using vitamin D supplementation
• using drugs that interfere on vitamin D metabolism (corticosteroids, anticonvulsants)
• illicit drug use
• diseases such as chronic renal failure (serum creatinine greater than 2.0 mg/dl)
• liver cirrhosis
• alcoholism
• dementia
• malignant disease that compromises the 5-year survival,
• digestive tract (malabsorption) diseases
• BMI> 40 kg / m2

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups, including a placebo group

vitamin D3

Experimental group

Description:

supplementation of 100.000 IU of vitamin D3

Treatment:

Dietary Supplement: supplementation of 100.000 IU of vitamin D3

Placebo pill

Placebo Comparator group

Description:

Placebo

Treatment:

Dietary Supplement: placebo pill