Surgical Approach for Retrorectal Tumors Cohort (SART cohort)

University Hospital Center (CHU)

Status: Completed

Conditions: Malignant Tumor

Treatments: Procedure: Resection of the retrorectal tumor

Study type: Observational

Funder types: Other

Identifiers

NCT04757103

RECHMPL21_0093

Details and patient eligibility

About

Aim of the study :

To evaluate postoperative outcomes of all surgical approach for retrorectal tumors.

Methods :

From 2005 to 2020, all consecutive patients who underwent surgery for a retrorectal tumor in two referral tertiary center were prospectively collected.

Considering our exlusion criterias, data from XX patients were analyzed. The cohort was separated into 2 groups according to tumor localization regarding the third sacral vertebra.

Short and longterm outcomes were compared between the two groups.

Primary outcome :

90 days postoperative morbidity rate

Full description

Retro-rectal tumors are a group of heterogeneous and rare lesions. The actual incidence has been estimated to be approximately one case per 40,000 admissions. It is most often a benign tumor that affects young women and the origin is congenital in 60% of cases. The most common benign lesion is a tailgut cyst. Chordoma is the most common malignant lesion. They are mostly asymptomatic or pauci-symptomatic. This is why their diagnosis is regularly accidentaly after a morphological examination such as an abdominal ultrasound or a CT scan. MRI is the gold standard for determining the structure of the lesion, its origin, its topography, its extension in relation to adjacent organs, parameters that are essential to define the type of surgery and its approach.

When a retro-rectal tumor is diagnosed, the standard treatment is surgical resection. A biopsy is not helpful if there is no suspicion of a degenerate lesion. Usually, lesions located under the third sacral vertebra (S3) are approached by dorsal transsacrococcygeal, perineal or combined approach (abdominal and perineal approach) while those located above S3 the approach is abdominal (laparotomy or laparoscopy). As these lesions are, in the majority of cases, benign, the functional impact of surgery is essential. Based on our experience in minimally invasive surgery and in particular in retro-rectal tumors, laparoscopy has become our first-line approach regardless of the location of the lesion compared to S3. Our hypothesis is that the minimally invasive approach is reliable, safe and allows satisfactory histological results to be obtained while limiting postoperative pain and functional sequelae.

Enrollment: 21 patients

Sex: All

Ages: 18 to 99 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient presenting a retrorectal tumor
• Surgical procedure between 01/01/2005 and 31/12/2020

Exclusion criteria

• age < 18 years old
• Patients presenting a rectal tumor
• Patients presenting a rectal duplication

Trial design

21 participants in 2 patient groups

Above S3

Description:

Lesion located above the third sacral vertebra

Treatment:

Procedure: Resection of the retrorectal tumor

Below S3

Description:

Lesion located below the third sacral vertebra

Treatment:

Procedure: Resection of the retrorectal tumor