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Surgical Excision of the Fat Pad

L

Liverpool University Hospitals NHS Foundation Trust

Status

Completed

Conditions

Osteo Arthritis Knee

Treatments

Procedure: removal of fat pad
Procedure: non removal of fat pad

Study type

Interventional

Funder types

Other

Identifiers

Details and patient eligibility

About

Introduction:

The infrapatellar fat pad (Hoffa's fat pad) is a structure which is located intra-articularly. Its function is not well known. During knee replacement surgery, some surgeons would prefer removing the whole of the fat pad as this can improve exposure of the knee joint, as it can affect exposure of the knee joint which will in turn make the procedure slightly more efficient. Other surgeons would rather resect the minimum amount and preserve the bulk of the structure as anecdotally this is thought to decrease the level of post operative pain. This surgical step fat pad resection is a very small part of the whole total knee replacement procedure.

A previous retrospective review of patients whose fat pad had been removed showed that they were nearly twice as likely to experience postoperative pain (P = 0.0005), while another study showed that they are at a slight risk of patellar tendon shortening.

A randomised controlled trial of 68 patients did not show any difference in patella tendon length at six months and no difference in pain relief in both groups 3. However this study did not evaluate the functional outcome in both groups.

To our knowledge, there are no RCT looking at the effect of the excision or preservation of the fat pad in TKR and the functional outcomes post operatively.

Study Hypothesis:

Excision of Hoffa's fat pad during total knee replacement surgery does not affect functional outcome, pain level after surgery or the patella tendon length at either one or two years.

Full description

RCT of excision or preservation of fat pad in TKR and the functional outcomes post operatively

Enrollment

154 patients

Sex

All

Ages

18+ years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • 1- Primary total knee replacement for knee osteoarthritis

Exclusion criteria

  1. Revision Surgery.
  2. Primary Knee Replacement for pathologies other than Osteoarthritis.
  3. Previous knee fractures around the knee.
  4. Previous confirmed intra-articular infections.
  5. Non English speaking/reading patients.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Double Blind

154 participants in 2 patient groups

Non removal of fat pad
Active Comparator group
Description:
Non removal of fat pad
Treatment:
Procedure: non removal of fat pad
Removal of fat pad
Active Comparator group
Description:
Removal of fat pad
Treatment:
Procedure: removal of fat pad

Trial contacts and locations

1

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Central trial contact

Antony Howard; Jo Banks

Data sourced from clinicaltrials.gov

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