Surgical Management and Outcome of Tethered Cord Syndrome

Assiut University

Status: Not yet enrolling

Conditions: Tethered Cord Syndrome

Treatments: Procedure: Detethering of the spinal cord

Study type: Observational

Funder types: Other

Identifiers

NCT05579795

Tethered Cord Syndrome

Details and patient eligibility

About

The aim of this study is to assess surgical management and outcome of Tethered cord syndrome

Full description

Tethered cord syndrome (TCS) is a developmental abnormality of the neuroaxis which is usually diagnosed in childhood. The actual tethering has been attributed to a variety of pathologic entities, including a thickened tight filum terminale , intradural lipomas with or without a connecting extradural component, intradural fibrous adhesions, diastematomyelia, and adherence of the neural placode following previous closure of a myelomeningocele. However, sufficient differences in the mode of onset, clinical manifestations, and outcome exist between pediatric and adolescent patients with tethered cord to warrant a more detailed analysis of the adult syndrome. The most problematic technical consideration in surgery for the release of the tethered cord is how to preserve functioning neural elements and rebuild the dural sac to avoid CSF leak. The purpose of this study is to review causes of Tethered cord, clinical presentation, diagnostic tools, treatment options and outcome in school-aged children, adolescents, and young adults with Tethered cord.

Enrollment: 35 estimated patients

Sex: All

Ages: 1 to 16 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients with Tethered cord syndrome presenting at our institute
• Patients with spinal dysraphism
• Lipomyelomeningocele with Tethered cord
• patients presented with neurological deficit after lipomyelomeningocele repair due to Tethered cord
• patients presented with neurological deficit after myelomeningocele repair due to Tethered cord
• Diastematomyelia with Tethered cord - Tethered cord due to filum terminale.
• Tethered cord due to fibrous adhesions

Exclusion criteria

• Asymptomatic Patients with Tethered cord discovered accidentally