Surgical Site Infiltration Using Ketamine Versus Bupivacaine for Analgesia in Post-operative Appendectomy Operation

Sohag University

Status and phase: Completed; Early Phase 1

Conditions: Appendicitis Acute

Treatments: Drug: Ketamine Versus Bupivacaine

Study type: Interventional

Funder types: Other

Identifiers

NCT05097118

Soh-Med-21-10-03

Details and patient eligibility

About

surgical site infiltration using ketamine versus Bupivacaine for analgesia in post-operative Appendectomy operation by Ketamine versus Bupivacaine

Enrollment: 60 patients

Sex: All

Ages: 14 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 60 adult patients with ASA physical physical status class 1 and class 2 undergoing uncomplicated appendectomy under general anesthesia

Exclusion criteria

• Patient refusal
• drug abuse
• Patient with neurological, psychiatirc or neuromuscular disease
• chronic pain on medicine
• known allergy to the study medicine
• Infection at the site of infiltration

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Group of Ketamine injection

Experimental group

Description:

Ketamine infiltration for post operative analgesia

Treatment:

Drug: Ketamine Versus Bupivacaine

Group of Bupivacaine injection

Experimental group

Description:

Bupivacaine infiltration for post operative analgesia

Treatment:

Drug: Ketamine Versus Bupivacaine