Surgical Strategy for Head and Neck Adenoid Cystic Cancer

Shanghai Jiao Tong University

Status: Completed

Conditions: Adenoid Cystic Carcinoma

Treatments: Procedure: surgery

Study type: Observational

Funder types: Other

Identifiers

NCT06778915

2024HNRT02

Details and patient eligibility

About

To investigate the relationship between surgical margins and outcomes across different tumor stages, in order to provide evidence and guidance for refining stage-specific surgical approaches.

Full description

Adenoid cystic carcinoma of the head and neck (HNACC) presents unique surgical challenges due to its propensity for perineural spread and proximity to critical craniofacial structures. While surgical resection remains the cornerstone of treatment, determining the optimal extent of resection to balance oncologic control and functional preservation requires further investigation. The investigator aimed to investigate the relationship between surgical margins and outcomes across different tumor stages, in order to provide evidence and guidance for refining stage-specific surgical approaches.

Enrollment: 309 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who underwent surgical resection with curative intent and PORT.

Exclusion criteria

• underwent only biopsy, presented with distant metastases or second primary malignancies at initial diagnosis, had incomplete clinical or histopathologic data, or had histologic evidence of high-grade transformation.