Surgical Stress and Intracorporeal Anastomosis

Federico II University

Status: Completed

Conditions: Laparoscopic Right Colectomy

Treatments: Procedure: Laparoscopic right colectomy

Study type: Interventional

Funder types: Other

Identifiers

NCT03422588

Intrastress-unina

Details and patient eligibility

About

The short-term advantages of minimally invasive colon resection have been well established in several randomized trials. A major factor in the development of morbidity is the surgical stress response with subsequent increased demand on the patient's reserves and immune competence. Although the advantage in term of stress response of laparoscopic surgery over open surgery has been widely reported, little is known about the role of Intracorporeal anastomosis.

In an attempt to evaluate the surgical stress response after totally laparoscopic right colectomy a comparative study has been designed.

Two surgical procedures will be evaluated:

• Totally laparoscopic right colectomy with intracorporeal anastomosis (Experimental group)
• Laparoscopic assisted right colectomy with extracorporeal anastomosis (Control group).

Enrollment: 20 estimated patients

Sex: All

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

All elective laparoscopic right colectomy for cancer

Exclusion criteria

Urgent procedures Immune depressant therapy Immune depressant disease Post-operative Complications

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 2 patient groups

Intracorporeal

Experimental group

Description:

Totally laparoscopic right colectomy with intracorporeal anastomosis

Treatment:

Procedure: Laparoscopic right colectomy

Extracorporeal

Active Comparator group

Description:

Laparoscopic assisted right colectomy with extracorporeal anastomosis

Treatment:

Procedure: Laparoscopic right colectomy