Surgical Treatment of Marfan Syndrome With Subluxation Lens

Zhejiang University

Status: Active, not recruiting

Conditions: Marfan Syndrome; Lens Subluxation or Dislocation

Treatments: Procedure: surgical treatment of Marfan Syndrome with subluxation lens

Study type: Observational

Funder types: Other

Identifiers

NCT05578469

2022-0765

Details and patient eligibility

About

To analyze the postoperative visual effects, and to compare the safety and efficacy of different surgical treatment with of Marfan Syndrome with subluxation lens.

Enrollment: 50 estimated patients

Sex: All

Ages: 8 to 55 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1. Patients diagnosed with MFS according to the revised Ghent etiology.
2. refractive errors difficult to correct.
3. pupillary block glaucoma caused by severe dislocation of the lens

Exclusion criteria

Keratoconus, late glaucoma, uveitis, history of traumatic lens dislocation, and preoperative retinal rupture with or without retinal detachment (RD)

Trial design

50 participants in 2 patient groups

posterior chamber intraocular lens(IOL) implantation with a Cionni capsular tension ring (CTR)

Treatment:

Procedure: surgical treatment of Marfan Syndrome with subluxation lens

sutured scleral fixation of posterior chamber IOL/ posterior chamber IOL and CTR

Treatment:

Procedure: surgical treatment of Marfan Syndrome with subluxation lens