Surgical Wound Infection Prevention Bundle in Patients Undergoing Coronary Bypass Graft Surgery

Sohag University

Status: Not yet enrolling

Conditions: Infection Due to Coronary Artery Bypass Graft (Diagnosis)

Treatments: Other: Surgical wound infection prevention bundle

Study type: Interventional

Funder types: Other

Identifiers

NCT07003750

soh-Med--25-4-05MS

Details and patient eligibility

About

estimate the utilization of locally customized surgical wound infection bundle to prevent and or control of infection in patients undergoing CABG surgery in Sohag

Enrollment: 200 estimated patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• coronary artery disease ,diebetes mellitus,hypertension,

Exclusion criteria

• patients who have cancer , immunocompromised patients, cardiac surgeries other than CABG

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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200 participants in 2 patient groups

group 1

Active Comparator group

Description:

* Preoperative: 1. Nightly CHG baths 2. Mupirocin nasal ointment twice daily for 2 to 5 days prior to surgery 3. Hair removal with clippers * Intraoperative: 1. Skin antisepsis with CHG solution 2. Standardized IV antibiotic doses at the following time points :within 5 to 60 minutes of the initial surgical incision, with initiation of cardiopulmonary bypass ,and every 3 hours intraoperatively for the duration of the case. * Postoperative : 1. The occlusive sternal dressing applied at time of chest closure and removed 48 hours postoperatively then daily dressing thereafter. 2. Daily postoperative linen change and minimize sternotomy exposure to home blankets

Treatment:

Other: Surgical wound infection prevention bundle

group 2

No Intervention group

Description:

* Preoperative: 1. Preoperative water and soap bath 2. Hair removal with razor * Intraoperative: 1. Skin antisepsis with betadine solution 2. One dose of antibiotic just before skin incision * Postoperative: 1. The occlusive sternal dressing removed 72 hours postoperatively then daily dressing 2. No specific concerns about linens change and home blankets exposure