Surveillance of Patients With Suspected Acute Myocardial Infarction That Receive Early Inhospital Thrombolysis With Metalyse

Boehringer Ingelheim

Status: Completed

Conditions: Myocardial Infarction

Treatments: Drug: Metalyse weight-adjusted

Study type: Observational

Funder types: Industry

Identifiers

NCT02194153

1123.16

Details and patient eligibility

About

Obtaining data on efficacy (e.g. complete ST-segment resolution) depending on the time of treatment initiation and safety of prehospital and early hospital thrombolysis with Metalyse® in a real life setting outside clinical trials.

Enrollment: 351 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Male and female patient with suspected myocardial infarction, e.g. during transportation to the hospital by ambulance. No patient younger than 18 years.
• Possibility of obtaining relevant information concerning indication or contraindication of thrombolysis in each patient
• Typical chest pain with a duration of more than 30 minutes
• Definite infarction signs in a 12-lead-ECG with ST-elevation > 0.1 millivolt (mV) in > 2 leads or recent left bundle branch block with typical clinical signs
• Symptom onset <= 6 hours

Exclusion criteria

• Patients older than 75 years (exception: patients appear much younger)
• Low body weight
• No persons under 18
• contraindications according to summary of product characteristics (SPC) for Metalyse

Trial design

351 participants in 1 patient group

Metalyse

Description:

Metalyse weight-adjusted

Treatment:

Drug: Metalyse weight-adjusted