Surveillance Study for Early Detection of Cholangiocarcinoma (CCA) in Primary Sclerosing Cholangitis (PSC)

Karolinska University Hospital

Status: Completed

Conditions: Primary Sclerosing Cholangitis; Cholangiocarcinoma

Treatments: Diagnostic Test: MR/MRCP

Study type: Observational

Funder types: Other

Identifiers

NCT03041662

2011/2:6

Details and patient eligibility

About

This observational study of a national cohort of 600 Swedish PSC patients include yearly MR/MRCP, biobanking of serum, plasma and blood, followup clinical data (interventions, symptoms, labs, colonoscopy). The aim is to collect a well characterized cohort of PSC patients and provide future possibilities to evaluate biomarkers for prognosis and early cancer detection.

Enrollment: 620 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Diagnosis of PSC by MR/MRCP
• Life expectancy >1 year
• Informed consent

Exclusion criteria

• Liver transplantation or on the waiting list
• Secondry SC
• Diagnosis of CCA