Survey of Patients Who Received Fertility Preservation Counseling and Underwent Testicular Tissue Cryopreservation Prior to Gonadotoxic Treatment During Childhood or Peripuberty (QUALIFERT)

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Status: Invitation-only

Conditions: Satisfaction Survey; Fertility Perservation

Treatments: Other: Survey using a questionnaire.

Study type: Interventional

Funder types: Other

Identifiers

NCT07140549

2023/14JUI/263

Details and patient eligibility

About

Chemotherapy and radiotherapy can lead to spermatogonial stem cell depletion in pre- and peripubertal boys, potentially resulting in infertility during adulthood A testicular biopsy is considered a safe procedure performed in children prior to gonadotoxic treatment as part of a fertility preservation strategy. At the time of the procedure, parental involvement is essential-both in their role as legal guardians and due to the limited cognitive capacity of young boys to fully comprehend fertility preservation counseling.

Long-term follow-up is necessary to evaluate the impact on fertility outcomes, psychological well-being, and overall satisfaction. The aim of this survey is to assess the perceived impact of fertility preservation counseling and the physical and emotional effects of undergoing testicular biopsy in this population, with the goal of identifying opportunities to improve patient experience and clinical care for future patients.

Enrollment: 60 estimated patients

Sex: Male

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients who have participated in the fertility preservation program aged 18 years old and above

Exclusion criteria

• Deceased patients. Patients undergoing treatment for disease relapse. Patients suffering from a documented mental disorder.

Trial design

Primary purpose: Health Services Research

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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60 participants in 1 patient group

Patients who underwent gonadotoxic treatment for oncological or benign disease

Experimental group

Description:

This survey study aims to assess the long-term outcomes and patient satisfaction of men who underwent a fertility preservation procedure i.e., a testicular biopsy with cryopreservation of immature testicular tissue, during prepuberty or peripuberty at the Cliniques Universitaires Saint Luc (CUSL) since the start of the fertility preservation program in 2005. Participants will be asked about their current reproductive health status, their experience with the fertility preservation process, and their overall satisfaction with the care they received.

Treatment:

Other: Survey using a questionnaire.