Survival and Predictive Factors of Clinical Outcome in Patients With Acquired Brain Injury

Charles University, Czech Republic

Status: Completed

Conditions: Acquired Brain Injury

Study type: Observational

Funder types: Other

Identifiers

NCT05968911

ABI_UVN

Details and patient eligibility

About

The prediction of the final neurological and functional status of patients with acquired brain injury remains very uncertain despite the findings of current medicine. The aim of the study is to evaluate the clinical outcomes in patients with the most severe degree of brain injury hospitalized in the long-term intensive care unit of the Military University Hospital Prague.

Full description

The prediction of the final neurological and functional status of patients with acquired brain injury remains very uncertain despite the findings of current medicine. Current medical knowledge is particularly limited in patients with the most severe brain injury who had to be tracheostomized and admitted to long-term intensive care unit. In the Czech Republic, there is a complete lack of data on clinical outcomes in these patients.

Some recent studies has not confirmed the long-standing better outcome in patients with traumatic brain injury compared to non-traumatic etiologies. The aim of the study is to evaluate the clinical outcomes in patients with the most severe degree of brain injury hospitalized in the long-term intensive care unit of the Military University Hospital Prague.

Enrollment: 211 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Acquired brain injury
• Initial Glasgow Coma Scale (GCS) score less than 8 points
• Tracheostomy for persistent impairment of consciousness

Exclusion criteria

• none

Trial design

211 participants in 2 patient groups

Trauma brain injury

Description:

Patients with acquired brain injury of traumatic etiology.

Non-trauma brain injury

Description:

Patients with acquired brain injury of non-traumatic etiology.