Survival and Quality of Life After Liver Transplantation in Patients Aged 65 and Over (LT 65+)

Gérond'if

Status: Enrolling

Conditions: Patients Suitable for a Liver Transplant

Study type: Observational

Funder types: Other

Identifiers

NCT04754503

2020-A03063-36

Details and patient eligibility

About

The main objective of this non-interventional, single-center study is to assess survival and associated factors at 1 year in patients aged 65 and over who received liver transplantation

Full description

The expected benefits of this study are to identify the preoperative risk factors of mortality from liver transplant failure in patients aged 65 and over (90-day mortality and 1 and 3-year survival) will allow better selection. candidates for this age group. In the current context of organ shortage, this study should make it possible to reduce the number of risky transplants and thus improve the allocation of grafts.Inclusion of patients who meet the inclusion criteria will be carried out during their hospitalization in the surgical department of the hepato-bilary center.

Included patients will receive a standardized geriatric assessment in addition to the usual assessment for a liver transplant.

The geriatric assessment will be carried out and conducted as follows: geriatric scores and quality of life questionnaires. Two geriatricians will perform the physical examination and blindly estimate each other's probability of survival at 90 days using a Likert scale.

Geriatricians will be blinded to hepatic data (reasons for transplantation). The consultation as well as the completion of the questionnaire will be carried out during the pre-transplantation assessment.

Survival and quality of life will be assessed at 3 and 12 months post-transplantaion.

Enrollment: 125 estimated patients

Sex: All

Ages: 65+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Candidates for liver transplantation
• Having expressed non-oppostion to his participation in study and documented in his medical file
• With social coverage

Exclusion criteria

• Emergency transplant patients
• Patient already included in another study
• Patient under guardianship or curatorship
• Expressing his opposition to participate in the study