Swallowing, Speech and Quality of Life of Patients With Carcinoma of the Oropharynx

Centre Hospitalier Universitaire de Saint Etienne

Status: Terminated

Conditions: Squamous Cell Carcinoma of the Oropharynx

Treatments: Procedure: Ability to swallow, speak and quality of life

Study type: Observational

Funder types: Other

Identifiers

NCT02552550

2012-A00904-39 (Other Identifier)

1208112

Details and patient eligibility

About

The curative treatment and organ preservation in advanced squamous cell carcinoma of the oropharynx is multimodal. It involves induction chemotherapy and depending on the response radio-chemotherapy or surgery. The combination of these methods has important functional consequences.

The aim of this prospective pilot study is to describe swallowing, speech, but also patients' quality of life before and after therapeutic management (existing studies measuring these functions after treatment but not before).

Full description

This study will not change the patient's treatment. This will just be an evaluation, before any treatment, his ability to swallow, speak then, as in normal practice, after 3, 6 and 12 months after treatment.

Enrollment: 12 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient with stage T3 or T4 squamous cell carcinoma of the oropharynx previously untreated.
• Performance status 0 or 1
• Tumor histology proving squamous cell carcinoma

Exclusion criteria

• Visceral metastases at initial assessment
• Contraindication to surgery and / or chemotherapy such as:
• A history of other cancer (except basal cell carcinoma skin or cervical cancer in situ)
• 2nd associated cancer

Trial design

12 participants in 1 patient group

Ability to swallow, speak and quality of life

Description:

This will just be an evaluation, before any treatment, his ability to swallow, speak and quality of life then, as in normal practice, after 3, 6 and 12 months after treatment.

Treatment:

Procedure: Ability to swallow, speak and quality of life