Sweet Corn and Carotenoids

University of Florida

Status: Active, not recruiting

Conditions: Carotenoids

Treatments: Dietary Supplement: White Sweet Corn; Dietary Supplement: Yellow Sweet Corn

Study type: Interventional

Funder types: Other

Identifiers

NCT06892444

IRB202500277

Details and patient eligibility

About

This study will assess the effect of daily yellow and white sweet corn intake on serum lutein and zeaxanthin concentrations. Skin carotenoid levels using the Veggie Meter will be assessed, and gastrointestinal symptoms and changes in fecal microbiota during a 4-week intervention period will be monitored.

Enrollment: 40 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Adults ≥ 18 years of age
• Able to provide written consent in English
• Baseline Veggie Meter score of ≤ 250 (Scale from 0 to 850)
• Willing to adhere to study procedures

Exclusion criteria

• Baseline Veggie Meter score of >250
• Corn allergy
• Current use of laxatives or antidiarrheal medications
• Previously or currently being treated for intestinal disease, including irritable bowel syndrome, Crohn's disease, ulcerative colitis, celiac disease, or gastrointestinal cancer
• Previous gastrointestinal surgery (e.g., gastric bypass, fundoplication, bowel resection)
• Current cancer treatment
• Current pregnancy
• Vegetarian diet
• Elite athletes or long-distance runners.
• Use of antibiotic drugs within 1 month of the screening visit.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Yellow Sweet Corn

Experimental group

Description:

1.5 cups of yellow sweet corn daily

Treatment:

Dietary Supplement: Yellow Sweet Corn

White Sweet Corn

Sham Comparator group

Description:

1.5 cups of white sweet corn daily

Treatment:

Dietary Supplement: White Sweet Corn