Swiss Atrial Fibrillation Cohort Study (SWISS-AF)
Status
Conditions
Details and patient eligibility
About
Swiss-AF is a prospective observational, multicentric cohort study in Switzerland. Overall, 2600 patients with documented atrial fibrillation aged >65 years will be included and followed on a yearly basis.
Yearly clinical examinations include a detailed questionnaire on personal characteristics, a resting electrocardiogram, neurocognitive function tests and questionnaires on disability and quality of life. Blood sampling and brain magnetic resonance imaging are scheduled at baseline and after 2 years of follow-up.
The main study aims of this long term prospective study are to increase our knowledge on structural brain damage and its changes over time in patients with atrial fibrillation, to gain additional insights on the incidence and underlying mechanisms of cognitive decline in patients with atrial fibrillation and to evaluate the interrelationships of structural and functional brain damage in this population.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- atrial fibrillation documented within the last 24 months
- age >=45 years
Exclusion criteria
- acute illness
- inability to provide informed consent
- Only short episodes of reversible forms of atrial fibrillation
Trial design
2,415 participants in 1 patient group
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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