Switching to E-cigarette After PCI (E-cig-PCI)

Samsung Medical Center

Status: Completed

Conditions: Coronary Artery Disease

Treatments: Behavioral: Smoking cessation; Behavioral: Switching to E-cigarette

Study type: Observational

Funder types: Other

Identifiers

NCT06338761

E-cigarette PCI

Details and patient eligibility

About

Despite the increasing popularity of electronic cigarettes (E-cigarettes), the prognostic impact of switching to E-cigarettes in smokers with coronary artery disease (CAD) who underwent percutaneous coronary intervention (PCI) remains uncertain.

Full description

Recently, several studies have reported that, although lower than combustible cigarette users, E-cigarette users had a significantly higher risk of future myocardial infarction (MI) or cardiovascular disease compared with non-smokers or quitters. However, because all previous studies has focused on the general healthy population, these results cannot be extrapolated for patients who already proven atherosclerotic cardiovascular disease (ASCVD), such as undergoing percutaneous coronary intervention (PCI) for coronary artery disease (CAD). Although Busch et al. previously reported that a significant minority of patients are using E-cigarettes post-acute coronary syndrome smokers, a paucity of data exists regarding the impact of such transitions on clinical outcomes in current smoker patients with CAD who have undergone PCI. In light of these considerations, the current study sought to address this gap in knowledge by evaluating the prognostic implications of smoking habit changes, including E-cigarette use, among CAD patients with current smoking status following PCI.

Enrollment: 17,973 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients who underwent health screening 3 years before and after the PCI

Exclusion criteria

• history of cancer
• history of ischemic stroke
• died within the first 3 months of follow-up from the index date
• Newly developed acute MI or received additional PCI or CABG from the index PCI date to the study index date

Trial design

17,973 participants in 3 patient groups

Continued combustible cigarette use

Description:

continued combustible cigarettes users after PCI

Switching to E-cigarette

Description:

switching to E-cigarette users after PCI

Treatment:

Behavioral: Switching to E-cigarette

Quitter

Description:

quitters after PCI

Treatment:

Behavioral: Smoking cessation