Syrenity App for Depression (SYRA)

Indiana University

Status: Invitation-only

Conditions: Depressive Symptoms

Treatments: Other: Syrenity App

Study type: Interventional

Funder types: Other

Identifiers

NCT06408025

2023-0410 (Other Identifier)

22283

Details and patient eligibility

About

The goal of this clinical trial is to learn if the Syrenity mental health app reduces depressive symptoms when compared to a control condition. Secondarily, the trial will provide data on the usability and acceptability of the Syrenity app. The main questions it aims to answer are:

Does Syrenity reduce self-reported depressive symptoms compared to a waiting list control? How usable is the Syrenity app?

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• PHQ-9 >= 10
• Use an iPhone or Android
• Residing in the United States

Exclusion criteria

• PHQ-9 item 9 >= 2

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

300 participants in 2 patient groups

Syrenity App

Experimental group

Description:

The Syrenity App is a mental health app that has been designed to help improve mental health and well-being. The content on the app was created using cognitive-behavioral therapy principles. It uses both active and passive interventions. Active interventions are interventions where the user engages with the app in a back and forth dialogue (e.g., a conversation about restructuring unhelpful thoughts). Passive interventions meanwhile consist of text or videos that the user can read or watch and do not require dialogue with the app.

Treatment:

Other: Syrenity App

Waiting list control

No Intervention group

Description:

Those assigned to the waiting list control condition will complete weekly surveys as those assigned to the intervention group but will not have access to the Syrenity platform until after the the 6-week trial period.