System to Evaluate the Risk of Lymph Node Metastasis Preoperatively in Cervical Cancer

Fujian Maternity and Child Health Hospital

Status: Completed

Conditions: Cervical Cancer

Treatments: Procedure: surgery

Study type: Observational

Funder types: Other

Identifiers

NCT06032481

FujianMCHH-Xu01

Details and patient eligibility

About

The lymph node status is difficult to be assessed preoperatively, this study aimed to develop a scoring system for predicting the risk of LNM in cervical cancer patients before operation.

Full description

Lymph nodes metastasis (LNM) was proved to be a critical risk factor related to the survival to cervical cancer survival. However, preoperative pelvic magnetic resonance imaging (MR) or computed tomography (CT) tests are less sensitive to assess the risk of lymph node metastasis. PET-CT is too expensive and radiative to be widely used in clinical practice. A model was constructed based on clinical indicators to predict lymph node metastasis preoperatively, providing a reference for clinical treatment.

Enrollment: 426 patients

Sex: Female

Ages: 25 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of cervical cancer
• FIGO stage IB1-IIA1
• Undergone radical hysterectomy with pelvic lymphadenectomy
• Peformed pelvic MRI examination preoperatively

Exclusion criteria

• Had distant metastases diagnosed before or during the surgery
• Underwent neoadjuvant radiotherapy preoperatively
• Underwent neoadjuvant chemotherapy preoperatively
• Incomplete or inaccuratemedical records